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Cercetare - Imunogenetica
Cercetare

Cercetare

  1. Utilitatea variantelor genetice de risc pentru cancerul de prostata ca biomarkeri de progresie si severitate.
  2. Studierea bazelor moleculare ale aparitiei cancerului renal cu posibilitatea validarii de noi biomarkeri cu utilitate clinica, de diagnostic si prognostic.
  3. Studiul modului in care pacientii cu cancer renal metastazat raspund la tratamentul cu cele mai folosite medicamente actuale.
  4. Variante genetice de risc in evolutia cancerului vezical superficial spre recidiva si progresie.
  5. HLA si prognosticul in oncologie (cancer de colon, cancer mamar, cancer pulmonar).
  6. Imunoterapia in cancerul de vezica urinara.
  7. Rolul imunogeneticii tumorale in diagnosticul si monitorizarea diferitelor tipuri de cancer.

– Oncogene si expresia alelelor HLA in diferite tipuri de cancer (cancer renal, carcinom de vezica urinara, adenocarcinom de colon, cancer pulmonar, cancer mamar, cancer de col uterin, cancer hepatic, etc.). Eficienta stimularii imunitatii celulare in diferite tipuri de cancer.

  1. Imunogenetica imbatrinirii.
  2. Diagnosticul genetic molecular, imunologic si predictia raspunsului la terapia imunosupresoare in transplantul de organe solide.
  3. Reconstituirea imunologica si chimerismul – parametrii esentiali in evaluarea posttransplant medular.
  4. Crossmatch-ul virtual – aspecte clinice, imunogenetice si de prognostic in transplantul renal.
  5. Biologia Moleculara a rejetului acut sub-clinic si clinic in transplantul de organ solid.
  6. Biologia Moleculara a GVHD post transplant de celule hematopoietice periferice.
Logo-Credit-White

Laboratorul a fost acreditat de Federatia Europeana de Imunogenetica (EFI) in anul 2006.